<p>Contraception with estradiol valerate and dienogest: adherence to the method</p>
نویسندگان
چکیده
منابع مشابه
Estradiol valerate and dienogest: a new approach to oral contraception
Most combination oral contraceptives contain ethinyl estradiol and a progestin. A new and novel oral contraceptive formulation combines estradiol valerate (E2V) with dienogest (DNG) in a four-phase dosing regimen. 17β-estradiol is a naturally-occurring estrogen, and a contraceptive pill containing such an estrogen offers potential benefits with regard to metabolic side effects and adverse event...
متن کاملEstradiol valerate and estradiol valerate/dienogest (natazia) tablets: the first four-phasic oral contraceptive.
614 P&T® • November 2010 • Vol. 35 No. 1
متن کاملAn overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE). E(2)-containing combined oral contraceptives (COCs) have demonstrated sufficient ovulation inhibition and acceptable contraceptive efficacy. However, earlier formulations were generally associated with unacceptable bleeding profiles. Two E(2)V-containing preparations have bee...
متن کاملReview of the safety, efficacy and patient acceptability of the combined dienogest/estradiol valerate contraceptive pill
The aim of this review is to define the role of the combined dienogest (DNG)/estradiol valerate (E2V) contraceptive pill, in terms of biochemistry, metabolic and pharmacological effects and clinical application as well. E2V is the esterified form of 17β-estradiol (E2), while dienogest is a fourth-generation progestin with a partial antiandrogenic effect. The cycle stability is achieved with 2 t...
متن کاملNoncontraceptive benefits of the estradiol valerate/dienogest combined oral contraceptive: a review of the literature
Combined oral contraceptives formulated to include estradiol (E2) have recently become available for the indication of pregnancy prevention. A combined estradiol valerate and dienogest pill (E2V/DNG), designed to be administered using an estrogen step-down and a progestin step-up regimen over 26 days of active treatment followed by 2 days of placebo (26/2-day regimen), has also undergone resear...
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ژورنال
عنوان ژورنال: Open Access Journal of Contraception
سال: 2019
ISSN: 1179-1527
DOI: 10.2147/oajc.s204655